CyberColloids

E 463 Hydroxypropyl Cellulose – Eu Specifications

COMMISSION REGULATION (EU) No 231/2012 of 9 March 2012

Synonyms

Cellulose hydroxypropyl ether

Definition

Hydroxypropylcellulose is cellulose obtained directly from strains of fibrous plant material and partially etherified with hydroxypropyl groups

Einecs:

Chemical name: Hydroxypropyl ether of cellulose

Chemical formula: The polymers contain substituted anhydroglucose units with the following general formula:

C 6 H 7 O 2 (OR 1 )(OR 2 )(OR 3 ), where R 1 , R 2 , R 3 each may be one of the following:

— H

— CH 2 CHOHCH 3

— CH 2 CHO(CH 2 CHOHCH 3 )CH 3

— CH 2 CHO[CH 2 CHO(CH 2 CHOHCH 3 )CH 3 ]CH 3

Molecular weight: From about 30 000 to 1 000 000

Assay: Content not more than 80,5 % of hydroxypropoxyl groups (-OCH 2 CHOHCH 3 ) equivalent to not more than 4,6 hydroxypropyl groups per anhydroglucose unit on the anhydrous basis

Description

Slightly hygroscopic white or slightly yellowish or greyish odourless and tasteless, granular or fibrous powder

Identification

Solubility: Swelling in water, producing a clear to opalescent, viscous, colloidal solution. Soluble in ethanol. Insoluble in ether

Gas chromatography: Determine the substituents by gas chromotography

pH: Not less than 5,0 and not more than 8,0 (1 % colloidal solution)

Purity

Loss on drying: Not more than 10 % (105 °C, 3 hours)

Sulphated ash: Not more than 0,5 % determined at 800 ± 25 °C

Propylene chlorohydrins: Not more than 0,1 mg/kg

Arsenic: Not more than 3 mg/kg

Lead: Not more than 2 mg/kg

Mercury: Not more than 1 mg/kg

Cadmium: Not more than 1 mg/kg